Combining machine learning with multiscale modeling creates robust predictive models that integrate underlying physics to manage ill-posed problems and can provide insights into disease mechanisms and treatment strategies.
Published in November 2019, this perspective review argues that breakthrough data collection in biology and medicine requires new analysis strategies. The authors contend that machine learning and multiscale modeling are complementary and demonstrate how their integration can produce physics-aware predictive models that handle massive, heterogeneous datasets.
- Impact 30%
- 49
- Evidence 25%
- 100
- Scale 20%
- 35
- Confidence 15%
- 100
- Recency 10%
- 83
Updated Jul 13, 2026 · TRV-2026-0204
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