TruaceTracing the truth around AIThursday, August 27, 2026
The Index

What the evidence says.What the public feels.

Ranks distinct AI gain and problem claims from the published record. Scores reward impact, independent source strength, scale, confidence, and recency.

1,169 results
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AI gains · 649

69
GainHealth· Newly added· Evidence: Moderate (1 source)

Automated AI quantification of pulmonary artery-to-vein volume difference achieved the highest discrimination for high/intermediate-high risk acute pulmonary embolism with low missed-diagnosis risk.

Researchers retrospectively analyzed 134 acute pulmonary embolism cases from April 2023 to March 2024, using commercial AI software to automatically measure a new biomarker, pulmonary artery-to-vein volume difference, alongside traditional CTPA parameters to stratify high/intermediate-high versus lower risk.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%100

Updated Aug 27, 2026 · TRV-2026-0909

69
GainHealth· Newly added· Evidence: Moderate (1 source)

Transfer learning enhanced AI lesion detection performance when models were adapted from one regional DBT database to another.

A study tested YOLO-based AI models for breast lesion detection on digital breast tomosynthesis using a 94-patient Western database from the Cancer Imaging Archive and a 157-patient Eastern database from a single medical center, with lesions grouped into six types.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%100

Updated Aug 27, 2026 · TRV-2026-0908

69
GainHealth· Newly added· Evidence: Moderate (1 source)

Integrated machine learning models using CT radiomics and clinical predictors achieved accurate preoperative prediction of synchronous liver metastasis in pancreatic ductal adenocarcinoma in validation, intended to assist decisions on surveillance versus biopsy or neoadjuvant therapy for indeterminate subcentimeter CT-

In a retrospective study of 340 pancreatic ductal adenocarcinoma patients, investigators developed machine learning models combining CT radiomics and clinical predictors to predict synchronous liver metastasis preoperatively. In an independent validation cohort of 102 patients, the best linear model (LDA) reached AUC 0.828 and the nonlinear model (MLP) reached AUC 0.822, both showing good calibration with Hosmer-Lemeshow P values of 0.551 and 0.682.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%100

Updated Aug 27, 2026 · TRV-2026-0907

69
GainHealth· Newly added· Evidence: Moderate (1 source)

Systematic review and meta-analysis of 15 brain tumor studies found deep learning synthesis of postcontrast T1-weighted MRI from precontrast sequences alone is technically feasible with high whole-image similarity.

Researchers systematically reviewed 41 studies through January 2025 that used deep learning to generate synthetic postcontrast T1-weighted MRI from precontrast images alone, aiming to reduce gadolinium use. Most work was in neuroimaging, using GANs and CNNs, and a targeted meta-analysis of 15 brain tumor studies reported high whole-image similarity metrics.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%100

Updated Aug 27, 2026 · TRV-2026-0904

AI problems · 520

68
ProblemHealth· Stable· Evidence: Moderate (1 source)

Machine learning's black-box nature has hindered clinical adoption of mortality prediction models for non-dialysis CKD despite their clinical importance.

Researchers developed and validated an interpretable machine learning model to predict 5-year all-cause mortality in non-dialysis chronic kidney disease using data from 1,858 patients in the KNOW-CKD prospective cohort, with 94 deaths observed. The CatBoost model achieved AUC 0.813 versus 0.747 for logistic regression, and a simplified version using age, eGFR, albumin, urine protein-to-creatinine ratio, and total calcium retained AUC 0.795 in an external cohort of 348 patients.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%96

Updated Aug 8, 2026 · TRV-2026-0688

68
ProblemHealth· Stable· Evidence: Moderate (1 source)

AI tools used in healthcare can make errors that result in patient harm, with responsibility difficult to assign because decisions are distributed across human and technological agents.

The peer-reviewed article examines responsibility gaps when AI tools in healthcare cause patient harm. It notes that traditional models struggle because decisions are spread across clinicians, developers, institutions and the AI systems themselves.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%96

Updated Aug 8, 2026 · TRV-2026-0686

68
ProblemHealth· Stable· Evidence: Moderate (1 source)

Users also reported risks from ChatGPT mental health conversations, including exposure to incorrect health advice, overly validating responses, and privacy concerns.

Researchers analyzed Reddit posts and comments about mental health conversations with ChatGPT to understand how large language models are being used for support outside clinical settings. By October 2025, they found users described ChatGPT as accessible and non-judgmental, providing emotional support, validation, and practical help like navigating difficult conversations and preparing for therapy.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%96

Updated Aug 7, 2026 · TRV-2026-0681

68
ProblemLifestyle· Stable· Evidence: Moderate (1 source)

Users of the Replika companion chatbot experienced AI-induced sexual harassment including unsolicited sexual advances and persistent boundary violations, leading to discomfort and privacy concerns.

A peer-reviewed study published October 16, 2025 examined user reviews of the Replika companion chatbot to investigate reports of inappropriate sexual behavior. From 35,105 negative Google Play Store reviews, researchers identified 800 cases for thematic analysis.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%96

Updated Aug 7, 2026 · TRV-2026-0680

Recomputed live from the record · Aug 27, 2026, 6:44 PM