TruaceTracing the truth around AIThursday, August 27, 2026
The Index

What the evidence says.What the public feels.

Ranks distinct AI gain and problem claims from the published record. Scores reward impact, independent source strength, scale, confidence, and recency.

1,168 results
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AI gains · 649

74
GainHealth· Newly added· Evidence: Moderate (1 source)

Applying FDA-cleared SubtleHD enhancement to already diagnostic-quality T1 MRI improved Alzheimer's disease classification performance and allowed models trained on only 70% of enhanced data to match full-data standard-of-care performance.

A retrospective study of 2293 ADNI brain MRIs plus 270 external NACC scans tested whether SubtleHD, an FDA-cleared deep learning enhancement tool, could improve downstream Alzheimer's classification when applied to already diagnostic-quality 1.5T T1-weighted images. ResNet34 and DenseNet121 models trained on enhanced images outperformed those trained on standard-of-care images on internal and external tests.

Impact 30%69
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%98

Updated Aug 15, 2026 · TRV-2026-0769

74
GainHealth· Stable· Evidence: Moderate (1 source)

Solvent extraction of urine analyzed by GC-MS and XGBoost distinguished bladder cancer patients from controls with AUROC 0.869 and 85% balanced sensitivity and specificity using an 8-metabolite panel.

On 2026-08-07, researchers reported a urine-based test for urothelial bladder cancer that combines solvent extraction, GC-MS profiling, and machine learning. In 100 participants, an XGBoost model using an 8-metabolite panel achieved AUROC 0.869, improving on classical statistics at 0.752, with 85% balanced sensitivity and specificity.

Impact 30%69
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%97

Updated Aug 10, 2026 · TRV-2026-0728

74
GainHealth· Rising· Evidence: Moderate (1 source)

AI-based machine learning applied to cholangioscopy images achieved high pooled diagnostic performance for indeterminate and malignant biliary strictures, with 95% sensitivity and 88% specificity.

By August 2026, researchers published a systematic review and meta-analysis of AI combined with digital cholangioscopy for indeterminate and malignant biliary strictures. The analysis pooled five studies totaling 675 lesions and 2,685,674 images, finding pooled sensitivity of 95%, specificity of 88%, and SROC accuracy of 97% for AI-assisted diagnosis.

Impact 30%69
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%96

Updated Aug 7, 2026 · TRV-2026-0679

74
GainHealth· Stable· Evidence: Moderate (1 source)

A Bi-LSTM and CNN fusion model combining text and visual data achieved 91.3% precision and 90.1% F-score on emotion recognition and up to 85.32% accuracy on depression classification, outperforming single-modal baselines.

A peer-reviewed study published August 6, 2026 proposes a deep learning framework for dynamic mental health assessment that fuses text and visual modalities. The model uses Bi-LSTM for text and CNN for images, trained on a jointly annotated dataset labeled with self-assessment questionnaires and expert annotations.

Impact 30%69
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%96

Updated Aug 7, 2026 · TRV-2026-0678

AI problems · 519

72
ProblemHealth· Stable· Evidence: Moderate (1 source)

Patients classified as Severe profile with early onset, 73.3% co-occurring psychiatric conditions and intense craving had poorer 3-month outcomes with only 36.7% abstinence and steep return to use.

In a retrospective study of 102 patients at a tertiary care center in India, researchers used k-means clustering on eight biopsychosocial baseline variables to derive three AUD profiles. By the August 2026 publication date, they reported Late-Onset, High-Functioning, and Severe groups with differing 3-month abstinence rates corroborated by GGT levels and bootstrap-assessed cluster stability.

Impact 30%63
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%96

Updated Aug 8, 2026 · TRV-2026-0687

72
ProblemHealth· Stable· Evidence: Moderate (1 source)

Probabilistic assessment of the sampled wells indicated high non-carcinogenic risk for children and infants, with 32.11% and 36.49% exceedance and fluoride identified as the dominant driver, alongside nitrate and fluoride above WHO guidelines at some sites.

On 2026-08-05, a peer-reviewed study reported analysis of 432 groundwater wells along Ghana's central coastal zone, combining hydrochemical indices with PCA, Self-Organising Maps and Monte Carlo probabilistic risk assessment. The work documented pronounced salinisation and mineralisation, with EC from 94.6 to 52,700 uS/cm and chloride up to 22,433 mg/l, and used machine learning to discriminate geogenic versus anthropogenic controls.

Impact 30%63
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%96

Updated Aug 6, 2026 · TRV-2026-0668

72
ProblemHealth· Stable· Evidence: Moderate (1 source)

Some ambiguous cases remained unresolved when investigator replies lacked actionable information, and cases with no reply after 48 hours still required deferral to offline manual review.

Researchers developed TrialTriage, a semiautonomous prescreening workflow on the n8n platform that uses large language model extraction from clinical narratives and investigator email replies plus a 7-criterion deterministic rule engine to classify phase I oncology trial eligibility, automatically emailing investigators when information is missing and reclassifying after reply capture.

Impact 30%63
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%96

Updated Aug 6, 2026 · TRV-2026-0666

72
ProblemHealth· Stable· Evidence: Moderate (1 source)

AI-driven diabetic retinopathy screening using ultra-widefield fundus images showed limited specificity of 72.5% in meta-analysis.

A systematic review and meta-analysis to February 9, 2025, evaluated artificial intelligence for diabetic retinopathy assessment using ultra-widefield color fundus images, which capture a larger retinal area without pupil dilation. Of 527 records, 17 studies were reviewed and four were meta-analyzed, all using Optos software, to estimate sensitivity and specificity for AI-driven screening.

Impact 30%63
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%94

Updated Jul 25, 2026 · TRV-2026-0564

Recomputed live from the record · Aug 27, 2026, 6:23 AM