Across 17 studies totaling 243,324 trauma patients, the best-performing ML model showed a small pooled AUC advantage over logistic regression for mortality prediction.
A systematic review and meta-research appraisal examined 20 studies comparing machine learning and logistic regression for trauma mortality prediction, with 17 studies (243,324 patients) in primary synthesis. The pooled within-study AUC difference favoring the best ML model was 0.026 (95% CI 0.009-0.043), 0.017 in co-primary analysis of studies reporting CIs, with extreme heterogeneity and a prediction interval crossing zero.
- Impact 30%
- 49
- Evidence 25%
- 95
- Scale 20%
- 35
- Confidence 15%
- 87
- Recency 10%
- 94
Updated Sep 13, 2026 · TRV-2026-1068
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