TruaceTracing the truth around AIThursday, August 27, 2026
The Index

What the evidence says.What the public feels.

Ranks distinct AI gain and problem claims from the published record. Scores reward impact, independent source strength, scale, confidence, and recency.

1,169 results
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AI gains · 649

71
GainHealth· Stable· Evidence: High (5 sources)

Random Forest survival model achieved comparable predictive accuracy to Cox regression on colon cancer mortality data, with low concordance error.

Published in 2017, this methods paper explored Random Forest as an alternative to Cox regression for survival analysis. Using 66,807 colon cancer cases from the SEER database, the authors built both a Cox model and a Random Forest model to derive mortality-associated risk factors and compared their predictive performance.

Impact 30%49
Evidence 25%100
Scale 20%35
Confidence 15%100
Recency 10%91

Updated Jul 13, 2026 · TRV-2026-0208

71
GainScience· Stable· Evidence: High (5 sources)

Combining machine learning with multiscale modeling creates robust predictive models that integrate underlying physics to manage ill-posed problems and can provide insights into disease mechanisms and treatment strategies.

Published in November 2019, this perspective review argues that breakthrough data collection in biology and medicine requires new analysis strategies. The authors contend that machine learning and multiscale modeling are complementary and demonstrate how their integration can produce physics-aware predictive models that handle massive, heterogeneous datasets.

Impact 30%49
Evidence 25%100
Scale 20%35
Confidence 15%100
Recency 10%91

Updated Jul 13, 2026 · TRV-2026-0204

71
GainScience· Rising· Evidence: High (5 sources)

AlphaFold provides a computational method that regularly predicts protein three-dimensional structures with atomic accuracy from amino acid sequence alone, even without homologous structures.

On July 15, 2021, Nature published the AlphaFold study describing a redesigned neural network that predicts the three-dimensional structure a protein will adopt based solely on its amino acid sequence. The authors reported validation in CASP14, where the model regularly achieved atomic accuracy even when no homologous structure was available and performed competitively with experimental structures.

Impact 30%49
Evidence 25%100
Scale 20%35
Confidence 15%100
Recency 10%91

Updated Jul 13, 2026 · TRV-2026-0203

71
GainCrime· Stable· Evidence: High (4 sources)

XAI-driven data mining applied to IoT ecosystems can detect anomalies and support automated security decisions through transparent and interpretable reasoning for smart city infrastructure.

Published February 20, 2026, this peer-reviewed survey in Cognitive Computation reviews XAI-driven data mining for self-defending IoT systems. It describes how IoT expansion in smart cities, healthcare, and industrial automation creates need for real-time, scalable security, and how XAI methods aim to detect anomalies and support automated decisions with transparent reasoning.

Impact 30%49
Evidence 25%100
Scale 20%35
Confidence 15%100
Recency 10%91

Updated Jul 13, 2026 · TRV-2026-0201

AI problems · 520

68
ProblemHealth· Newly added· Evidence: Moderate (1 source)

When used zero-shot to identify lumbar disc herniations on sagittal MRI, Gemini 3.1 Pro produced low specificity and a substantial false-positive burden, with T1+T2 input performing worse than T1-only.

Researchers tested Gemini 3.1 Pro in a zero-shot setting to detect lumbar disc herniations on sagittal MRI from 119 SPIDER cases (26% prevalence). Using only the mid-sagittal slice and a forced binary prompt, T1-only achieved 70% accuracy with 58% sensitivity and 74% specificity, while paired T1+T2 achieved 58% accuracy with 77% sensitivity and 51% specificity.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%97

Updated Aug 14, 2026 · TRV-2026-0758

68
ProblemHealth· Newly added· Evidence: Moderate (1 source)

Current AI toxicity models are limited by black-box opacity that lowers transparency and regulatory confidence, with most explainable AI applications still stuck at computational or preclinical stage.

On August 12, 2026, a review in the International Journal of Toxicology summarized AI and machine learning use in toxicological risk assessment to predict chemical toxicity and support regulatory decisions, noting that explainable AI methods like SHAP and LIME are being explored to make model decisions interpretable.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%97

Updated Aug 14, 2026 · TRV-2026-0757

68
ProblemHealth· Newly added· Evidence: Moderate (1 source)

Standard initial pathology of RRSO specimens missed serous (pre)malignancies in BRCA1/2 carriers, leaving occult STIC or HGSC undetected in patients who subsequently developed peritoneal HGSC.

By August 2026, a Histopathology study re-examined fallopian tube tissue from 19 BRCA1/2 carriers who had undergone risk-reducing salpingo-oophorectomy around age 40. Using deeper sections cut at 150 μm intervals and a deep learning model to support STIC detection, the team found occult STIC or HGSC in all patients who later developed peritoneal HGSC despite having no STIC or HGSC at initial diagnosis.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%97

Updated Aug 14, 2026 · TRV-2026-0755

68
ProblemHealth· Newly added· Evidence: Moderate (1 source)

When recommending musculoskeletal providers, LLMs at times provided inaccurate phone numbers and contact information, potentially preventing patients from reaching the appropriate clinic.

Researchers prompted ChatGPT, DeepSeek, and Gemini with standardized musculoskeletal complaints for Lynchburg, VA and Trumbull, CT, and judged whether recommended physicians were currently practicing locally in the relevant specialty and whether phone numbers were correct. By the August 13, 2026 publication date, ChatGPT was appropriate in all 17 recommendations, while Gemini and DeepSeek were appropriate in 43% and 40% of recommendations respectively.

Impact 30%49
Evidence 25%95
Scale 20%35
Confidence 15%87
Recency 10%97

Updated Aug 14, 2026 · TRV-2026-0752

Recomputed live from the record · Aug 27, 2026, 4:45 PM