Gradient-boosted machine learning predicted carbapenem MICs from resistance gene profiles with strong performance for imipenem and ertapenem, supporting AMR surveillance.
A One-Health study analyzed 30,554 E. coli whole-genome sequences from human, animal and environmental sources across 126 countries from 2000 to 2025, using AMRFinderPlus and MLST to map resistance genes and clones, and applied gradient-boosted machine learning to predict MICs from gene profiles and chromosomal features.
- Impact 30%
- 49
- Evidence 25%
- 95
- Scale 20%
- 85
- Confidence 15%
- 87
- Recency 10%
- 86
Updated Jul 29, 2026 · TRV-2026-0584
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