A prespecified EfficientNet plus Random Forest model classified gross pathology photographs to distinguish NIFTP from IEFVPTC with pooled AUC 0.788, sensitivity 0.588 and specificity 0.944 in 87 patients.
On August 26, 2026, a peer-reviewed study reported a proof-of-concept deep learning approach to distinguish two diagnostically challenging thyroid neoplasms, NIFTP and IEFVPTC, using gross pathology photographs from 87 patients. Using frozen pretrained CNN backbones and traditional classifiers with nested cross-validation, the prespecified EfficientNet plus Random Forest model achieved a pooled AUC of 0.788.
- Impact 30%
- 49
- Evidence 25%
- 95
- Scale 20%
- 35
- Confidence 15%
- 87
- Recency 10%
- 91
Updated Aug 28, 2026 · TRV-2026-0915
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