Nine machine learning models using baseline frailty index predicted motoric cognitive risk syndrome, with higher frailty linked to increased MCR risk in adults aged 45 and older.
Researchers analyzed 3388 CHARLS participants aged 45 and older across 2011 to 2015 to examine frailty and motoric cognitive risk syndrome. They built nine machine learning models using baseline frailty index to predict MCR risk and tracked changes in frailty status. By follow-up end, 127 participants (3.74%) developed MCR, with higher baseline FI, total FI, and change in FI associated with increased risk.
- Impact 30%
- 49
- Evidence 25%
- 95
- Scale 20%
- 35
- Confidence 15%
- 87
- Recency 10%
- 92
Updated Aug 31, 2026 · TRV-2026-0936
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