Fully automated AI-based lesion segmentation achieved excellent overlap and high quantitative agreement with expert manual delineation for lymphoma on whole-body FDG PET/CT.
By September 2026, researchers retrospectively evaluated a fully automated AI-based lesion segmentation tool using a hybrid 2D-3D nnUNet with ResNet18 backbone on whole-body FDG PET/CT scans from 72 lymphoma patients. Compared with manual delineations by experienced physicians, the model segmented 711 lesions versus 848 manual lesions and achieved DSC 89.2%, sensitivity 82.9, PPV 96.5, with strong correlations for PET metrics.
- Impact 30%
- 49
- Evidence 25%
- 95
- Scale 20%
- 35
- Confidence 15%
- 87
- Recency 10%
- 98
Updated Sep 30, 2026 · TRV-2026-1222
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