Integrating pathology foundation models and multimodal AI to connect histology, genomics, spatial biology and longitudinal monitoring enables evolution-aware prediction of lymph-node metastasis and recurrence risk in colorectal cancer.
Published August 14, 2026, this peer-reviewed synthesis argues that lymph-node metastasis prediction in colorectal cancer should move beyond static histology to clonal ecology, integrating computational pathology with evolutionary oncology and AI-enabled tracking of dominant and dormant subclones.
- Impact 30%
- 49
- Evidence 25%
- 95
- Scale 20%
- 35
- Confidence 15%
- 87
- Recency 10%
- 89
Updated Aug 16, 2026 · TRV-2026-0782
ace