PROBAST+AI: an updated quality, risk of bias, and applicability assessment tool for prediction models using regression or artificial intelligence methods
The Prediction model Risk Of Bias ASsessment Tool (PROBAST) is used to assess the quality, risk of bias, and applicability of prediction models or algorithms and of prediction model/algorithm studies. Since PROBAST’s introduction in 2019, much progress has been made in the methodology for prediction modelling and in the use of artificial intelligence, including machine learning, techniques. An update to PROBAST-2019 is thus needed. This article describes the development of PROBAST+AI. PROBAST+AI consists of two…
PROBAST+AI provides a unified tool that lets stakeholders assess quality, bias, and applicability of both regression and AI-based prediction models in healthcare.
The original 2019 PROBAST tool had become outdated given rapid progress in prediction modelling methodology and AI including machine learning.
Evidence
- Peer-reviewedBMJ2025-03-24
How should this claim be treated?
Truvace Impact Record TRV-2026-0537, v2: “PROBAST+AI: an updated quality, risk of bias, and applicability assessment tool for prediction models using regression or artificial intelligence methods.” Truvace, 2026-10-26. /record/TRV-2026-0537 (accessed at citation time). sha256 e3b5572e070d3562…
Calibration history
Every change to this record since certification, in the open.
Direction audit: the gain line stated no AI consequence and was removed; the problem line stated no AI consequence and was removed. Filed as context; not counted as a gain or a problem.
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