aceFully automated AI-based quantification of tumour volume on PSMA PET-CT images is associated with overall survival in prostate cancer
Introduction Artificial intelligence (AI)-based models can quantify tumour volume in positron emission tomography (PET) examinations using prostate specific membrane antigen (PSMA). It is, however, unknown whether this measurement of tumour volume contains prognostic information. The purpose of this study was to examine whether tumour volume measured by AI is associated with overall survival in patients with prostate cancer. Methods Patients who had undergone [ 18 F]PSMA-1007 PET-CT due to primary staging or bio…
In a retrospective study of 267 prostate cancer patients, tumour volume measured automatically by AI on PSMA PET-CT, with no manual correction, was linked to survival, and high whole-body volume carried a hazard ratio of 3.20 for death versus low.
The study was retrospective and single-centre, with a limited number of deaths, so the strength of evidence varied by site and subgroup; the authors say larger prospective cohorts with longer follow-up are needed.
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- Peer-reviewedClinical Physiology and Functional Imaging2026-11-01
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Truvace Impact Record TRV-2026-2414, v1: “Fully automated AI-based quantification of tumour volume on PSMA PET-CT images is associated with overall survival in prostate cancer.” Truvace, 2026-11-07. /record/TRV-2026-2414 (accessed on the day you copy it). sha256 71f0ff3dd4a2f727…
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