TRV-2026-1463Certified recordPeer-reviewed

Graph theory-based machine learning for automated fibromyalgia diagnosis using fMRI during an emotional task

Background Fibromyalgia (FM) is a multifaceted chronic pain disorder presenting with pain throughout the musculoskeletal system, alongside chronic fatigue,sleep disturbances, and cognitive impairments. Current diagnostic criteria primarily rely on symptom questionnaires, with no specific laboratory markers or definitive tests, making diagnosis subjective and often delayed. Moreover, the overlap with other central pain syndromes further complicates accurate diagnosis. Neuroimaging studies, particularly functional…

Health · Good Space — documented gain · certified 2026-10-15 · v1 · article view · machine-readable

Current reading — gain

A mixture-kernel support vector machine trained on graph-theory features from emotion-regulation brain regions best distinguished 32 fibromyalgia patients from 30 controls on sensitivity and AUC, suggesting a route to less subjective diagnosis.

What this doesn’t fix

The source states that small sample sizes make translating fMRI findings into reliable diagnostic tools challenging, and this study itself uses only 62 participants.

Evidence

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Truvace Impact Record TRV-2026-1463, v1: “Graph theory-based machine learning for automated fibromyalgia diagnosis using fMRI during an emotional task.” Truvace, 2026-10-15. /record/TRV-2026-1463 (accessed at citation time). sha256 7c29ae694a0311c3…

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