aceHow to apply artificial intelligence (AI) to facilitate and enhance MASH trials
Introduction Metabolic dysfunction-associated steatohepatitis (MASH) is one of the most common liver diseases, but thus far only two drugs (resmetirom and semaglutide) have received conditional approval for use. Successful MASH trials are thus highly desired to fill the therapeutic and evidence gap. Concurrently, AI has powered advances in multiple areas of medicine. We consider in this review the potential applications of AI to enhance MASH trials. Methods We conduct a narrative review of AI uses in MASH, with…
AI-based digital pathology models have been qualified by regulators for endpoint determination in MASH trials, with additional AI risk models and large language models applied to patient enrollment, recruitment and retention.
Evidence is presented as a narrative review of current and potential applications, not as new trial results measuring safety or efficacy outcomes.
Sources
- Peer-reviewedHepatology International2026-09-16
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Truvace Impact Record TRV-2026-1134, v2: “How to apply artificial intelligence (AI) to facilitate and enhance MASH trials.” Truvace, 2026-11-04. /record/TRV-2026-1134 (accessed on the day you copy it). sha256 1dd4cc58609217b0…
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Editorial pass: sharper headline; filed as context: no real AI gain or problem (gain activity_only, problem absent).
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