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TRUVACE RECORD VERSION record: TRV-2026-0983 version: 1 kind: certified reason: Certified into the record timestamp: 2026-09-05T06:04:17.255082Z status: published lens: p_space sector: labor headline: Unmasking bias in the evidence ecosystem: a panoramic analysis of 311,751 meta-analyses using an artificial intelligence agent-based approach dek: Traditional secondary meta-analysis workflows are highly labour-intensive, time-consuming, and difficult to update in real time. Currently, there is a lack of comprehensive artificial intelligence frameworks capable of automating the entire meta-analysis workflow, including literature screening, data extraction, and quality assessment. Furthermore, a large-scale structured database for systematically analysing the global landscape of published meta-analyses remains unavailable. In this viewpoint, we aimed to eva… gain_title: (none) problem_title: Currently, there is a lack of comprehensive artificial intelligence frameworks capable of automating the entire meta-analysis workflow, including literature screening, data extraction, and quality assessment. trace_subject: (none) gain_reading: (none) gain_evidence: (none) problem_reading: Currently, there is a lack of comprehensive artificial intelligence frameworks capable of automating the entire meta-analysis workflow, including literature screening, data extraction, and quality assessment. problem_evidence: (none) quick_read: Traditional secondary meta-analysis workflows are highly labour-intensive, time-consuming, and difficult to update in real time. Currently, there is a lack of comprehensive artificial intelligence frameworks capable of automating the entire meta-analysis workflow, including literature screening, data extraction, and quality assessment. In this viewpoint, we aimed to evaluate the feasibility of large language models in automating meta-analysis workflows and develop the Meta-Analysis Screening, Transformation and Evaluation Review Agent (MASTER) agent; establish a large-scale Unified Meta-Analysis Repository (UMAR) and perform an exploratory panoramic analysis of the current evidence ecosystem; and develop an Agent-based Secondary Meta-analysis Platform (ASAP), integrating these capabilities. Here, we provide an initial exploration of the technical feasibility and scalability of artificial intelligence-driven automated meta-analysis. limitation: tag: Evidence-backed problem key_points: Traditional secondary meta-analysis workflows are highly labour-intensive, time-consuming, and difficult to update in real time. | Currently, there is a lack of comprehensive artificial intelligence frameworks capable of automating the entire meta-analysis workflow, including literature screening, data extraction, and quality assessment. | Furthermore, a large-scale structured database for systematically analysing the global landscape of published meta-analyses remains unavailable. rundown: Traditional secondary meta-analysis workflows are highly labour-intensive, time-consuming, and difficult to update in real time. Currently, there is a lack of comprehensive artificial intelligence frameworks capable of automating the entire meta-analysis workflow, including literature screening, data extraction, and quality assessment. Furthermore, a large-scale structured database for systematically analysing the global landscape of published meta-analyses remains unavailable. In this viewpoint, we aimed to evaluate the feasibility of large language models in automating meta-analysis workflows and develop the Meta-Analysis Screening, Transformation and Evaluation Review Agent (MASTER) agent; establish a large-scale Unified Meta-Analysis Repository (UMAR) and perform an exploratory panoramic analysis of the current evidence ecosystem; and develop an Agent-based Secondary Meta-analysis Platform (ASAP), integrating these capabilities. sources: - peer_reviewed | Journal of Global Health | https://doi.org/10.7189/jogh.16.03029 | 2026-09-04 prev: 0000000000000000000000000000000000000000000000000000000000000000
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