Early Identification of Recovery Potential After Acute Brain Injury Using Functional Near-Infrared Spectroscopy
Background Accurate early prognostication in patients with acute brain injury remains a major challenge in neurocritical care. Conventional bedside assessments provide limited insight into long-term outcomes and may not fully capture preserved brain function that supports recovery. Functional neuroimaging can detect brain activity not evident at the bedside, but its use in intensive care remains constrained by cost, logistics, and the need for stronger evidence supporting its value. Functional near-infrared spec…
A machine learning model using bedside fNIRS functional connectivity during audio movie clips predicted 6-month functional outcome in ICU patients with acute brain injury with 81.3% balanced accuracy, outperforming clinical models.
Small single-center cohort of 33 patients with imbalanced outcomes limits generalizability and requires larger multicenter validation before clinical use.
Evidence
- Peer-reviewedNeurocritical Care2026-07-24
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Truvace Impact Record TRV-2026-0572, v1: “Early Identification of Recovery Potential After Acute Brain Injury Using Functional Near-Infrared Spectroscopy.” Truvace, 2026-07-26. /record/TRV-2026-0572 (accessed at citation time). sha256 062538012db179ab…
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