Children's medical imaging is underrepresented in AI development and testing, an expert panel review finds

Study title: Pediatric Artificial Intelligence in Radiology: Unmet Needs and Next Steps-<i>AJR</i> Expert Panel Review

On 2026-09-09, an AJR Expert Panel Narrative Review assessed the state of artificial intelligence in pediatric radiology, finding that while AI has transformed general radiology, pediatric imaging remains substantially underrepresented in development, validation, regulation, and implementation.

Read the study abstract

Artificial intelligence (AI) applications have transformed radiology, yet pediatric medical imaging remains substantially underrepresented in AI development, validation, regulation, and implementation. Unlike adults, children go through continuous physiologic and anatomic changes that require age-specific models trained on representative developmental data. However, pediatric AI is limited by scarce publicly available datasets, fragmented institutional data, rare diseases, heterogeneous reporting practices, and…

Pediatric Artificial Intelligence in Radiology: Unmet Needs and Next Steps-<i>AJR</i> Expert Panel Review
Real-time Magnetic Resonance Imaging of a child swallowing pineapple juice by Hirsch, F.W., Frahm, J., Sorge, I. et al. (2021). CC BY 4.0 · https://creativecommons.org/licenses/by/4.0

In brief

The gap matters because children need age-specific models and representative developmental data to ensure diagnostic accuracy and safety; without dedicated pediatric infrastructure, standards, and external validation, off-label adult models and biased datasets could compromise clinical outcomes, and reimbursement misalignment may further slow equitable adoption.

Main points

  1. Pediatric imaging requires age-specific models trained on representative developmental data due to continuous physiologic and anatomic changes in children.
  2. Development is constrained by scarce public datasets, fragmented institutional data, rare diseases, and heterogeneous reporting practices.
  3. Panel flags ethical and regulatory concerns including consent for secondary data use and off-label use of adult-trained models in children.

The problem

Pediatric medical imaging is substantially underrepresented in AI development and validation, with scarce datasets and off-label use of adult models risking bias and patient safety.

The rundown

The review notes children undergo continuous physiologic and anatomic changes that require age-specific models trained on representative developmental data, unlike adult populations.

It identifies additional barriers including ethical concerns around consent for secondary data use, off-label use of adult-trained AI models, need for postdeployment surveillance, and misaligned reimbursement that must be optimized to allow innovation.

Sources

  1. Peer-reviewedAmerican Journal of Roentgenology2026-09-09

The debate