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Artificial intelligence in ophthalmic optical coherence tomography angiography: a bibliometric analysis

Aim To analyze research landscapes, hotspots, and trends in artificial intelligence (AI) applied to ophthalmic optical coherence tomography angiography (OCTA) from 2015 to 2024, aiming to reveal global collaborations and guide future research. Methods We retrieved publications from Web of Science Core Collection using AI and OCTA-related search terms. After screening, 237 articles were analyzed with CiteSpace (version 6.3.R1) for co-citation, collaboration, and keyword burst analysis. Results Annual publications…

By the Truvace desk1 min read1 sourcePeer-reviewedTRV-2026-2024· cite & verify
Artificial intelligence in ophthalmic optical coherence tomography angiography: a bibliometric analysis
"Retinal Epithelial Cells (RPE) Grown on Scaffold" by National Institutes of Health (NIH) is marked with Public Domain Mark 1.0. To view the terms, visit https://creativecommons.org/publicdomain/mark/1.0/.

In brief

Researchers searched the Web of Science Core Collection for work on artificial intelligence and optical coherence tomography angiography published between 2015 and 2024. They analyzed 237 articles with CiteSpace and found publication volume rose rapidly from 2017, with China and the US the most productive countries.

The findings matter because they show where AI-enabled eye imaging research is concentrating, notably on diagnosing conditions such as diabetic retinopathy and glaucoma. The review itself is a map of the literature, so it does not show that these tools improve care in routine practice, and the authors call for broader clinical validation.

Main points

  1. The analysis covered 237 articles from 2015 to 2024, drawn from Web of Science Core Collection.
  2. China contributed 94 publications and the US 86, making them the most productive and influential countries.
  3. Main research themes were deep learning and vessel segmentation, diagnosis of diabetic retinopathy and glaucoma, and automated vascular quantification with multimodal imaging.
  4. The authors recommend robust, interpretable models, multi-center validation, and standardized imaging and analysis protocols.

The gain

AI combined with OCTA research has advanced automated, quantitative analysis of retinal vascular imaging, showing potential for diagnosing retinal and choroidal diseases.

The rundown

The study used CiteSpace version 6.3.R1 to run co-citation, collaboration, and keyword burst analyses. These methods were applied to reveal global collaboration patterns and research hotspots in AI-based OCTA.

Three research clusters emerged: deep learning algorithms for vessel segmentation, ocular disease diagnosis including diabetic retinopathy and glaucoma, and automated vascular quantification using multimodal imaging.

The authors say the goal is eventual widespread adoption of AI-OCTA in routine clinical practice. They say that requires large-scale multi-center clinical validation and standardized protocols.

Sources

  1. Peer-reviewedInternational Journal of Ophthalmology2026-10-18

The debate