AI model beats standard dosing models at predicting antibiotic levels in 39 patients
Researchers used nine published population pharmacokinetic models to simulate 90,000 daptomycin profiles in patients with infections, kidney transplants, or renal replacement therapy. They trained seven machine learning algorithms to predict 24-hour drug exposure (AUC 0-24), and CatBoost performed best.
Antimicrobial Agents and Chemotherapy
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