Pulmonary Artery-to-Vein Volume Difference: A New Imaging Biomarker for Risk Stratification in Acute Pulmonary Embolism
Rationale and objectives To propose a new imaging biomarker, the pulmonary artery-to-vein volume difference (PAVVD), and evaluate its efficacy in risk stratification of acute pulmonary embolism (APE) compared with traditional computed tomography pulmonary angiography (CTPA) parameters, as well as the impact of chronic pulmonary disease (CPD). Materials and methods This retrospective study included 134 patients with APE (high/intermediate-high risk, n = 46; intermediate-low/low risk, n = 88) from April 2023 to Ma…
Automated AI quantification of pulmonary artery-to-vein volume difference achieved the highest discrimination for high/intermediate-high risk acute pulmonary embolism with low missed-diagnosis risk.
Retrospective single-cohort design with 134 patients limits generalizability and requires external validation.
Evidence
- Peer-reviewedAcademic Radiology2026-08-25
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Truvace Impact Record TRV-2026-0909, v1: “Pulmonary Artery-to-Vein Volume Difference: A New Imaging Biomarker for Risk Stratification in Acute Pulmonary Embolism.” Truvace, 2026-08-27. /record/TRV-2026-0909 (accessed at citation time). sha256 9584d4b2b246203c…
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