Large Language Model Framework for Structured Biomarker Extraction and Triple-Negative Breast Cancer Identification From Pathology Reports: Development and Evaluation Study
Background: Triple-negative breast cancer (TNBC) is an aggressive molecular subtype of breast cancer that needs to be identified accurately from pathology reports to inform decision-making. Large language models (LLMs) have been reported to show great potential in the automatic extraction of important oncology information from unstructured medical text. Objective: We aimed to create and test an LLM-based approach for automatic biomarker extraction and TNBC subtype classification based on breast cancer pathology…
Prompt-engineered language models converted unstructured pathology reports into structured clinical features and identified triple-negative breast cancer patients automatically.
Evidence
- Peer-reviewedJMIR Formative Research2026-10-23
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Truvace Impact Record TRV-2026-2228, v1: “Large Language Model Framework for Structured Biomarker Extraction and Triple-Negative Breast Cancer Identification From Pathology Reports: Development and Evaluation Study.” Truvace, 2026-10-24. /record/TRV-2026-2228 (accessed at citation time). sha256 80d62eb75ddf642f…
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