aceMultimodal AI refines EAU risk stratification in patients undergoing radiotherapy for prostate cancer
Abstract The European Association of Urology (EAU) risk groups guide treatment decisions in prostate cancer using prostate-specific antigen (PSA), ISUP grade, and clinical stage, but do not incorporate histopathological image information. We evaluated a locked multimodal artificial intelligence (AI) model that integrates routinely available clinical variables (age, PSA, and ISUP grade) with deep-learning features extracted from diagnostic biopsy whole-slide images for predicting outcomes after radiotherapy (RT).…
Adding a multimodal AI score to EAU classification improved model fit and separated outcomes within EAU risk groups in 353 radiotherapy-treated men.
The AI score's improvement over EAU groups was not statistically significant in paired C-index comparisons, the risk stratification was exploratory, and prospective validation is needed.
Evidence
- Peer-reviewedScientific Reports2026-10-17
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Truvace Impact Record TRV-2026-1812, v1: “Multimodal AI refines EAU risk stratification in patients undergoing radiotherapy for prostate cancer.” Truvace, 2026-10-18. /record/TRV-2026-1812 (accessed at citation time). sha256 6bd918047e4b184a…
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