aceAutomated Bergmann-Kliesch Score assessment in testicular biopsies using artificial intelligence-based whole-slide image analysis: a retrospective monocentric development and validation study
Background The Bergmann-Kliesch Score is a histopathological grading system used to evaluate spermatogenesis in testicular biopsies, quantifying the fraction of seminiferous tubules containing elongated spermatids. It serves as a key parameter in the clinical process of men with non-obstructive azoospermia (NOA) undergoing testicular sperm extraction (TESE) for subsequent intracytoplasmic sperm injection (ICSI). Manual Bergmann-Kliesch Score assessment is time-consuming and subject to inter- and intraobserver va…
An AI pipeline automated Bergmann-Kliesch Score assessment from biopsy slide images and agreed strongly with pathologist reference scores on a held-out test set of 15 patients.
Evidence
- Peer-reviewedBasic and Clinical Andrology2026-10-06
How should this claim be treated?
Truvace Impact Record TRV-2026-1796, v1: “Automated Bergmann-Kliesch Score assessment in testicular biopsies using artificial intelligence-based whole-slide image analysis: a retrospective monocentric development and validation study.” Truvace, 2026-10-18. /record/TRV-2026-1796 (accessed at citation time). sha256 767464391b69fcc6…
Calibration history
Every change to this record since certification, in the open. None yet — the reading has held since it entered the record.
Certified into the record
How to verify without trusting this page
Fetch the canonical text of any version from /api/record/TRV-2026-1796 and hash it yourself — for example shasum -a 256 on the saved canonical field. The result must equal content_hash, and each version’s text ends with prev:followed by the prior version’s hash (version 1 chains to 64 zeros). If a single character of any version had been altered since certification, the chain would not reproduce.