Retrieval-to-abstraction LLM-assisted literature synthesis: Case demonstrations in digital health technology-enabled randomized controlled trial outcome reporting
Systematic reviews of randomized controlled trials (RCTs) support evidence-based clinical advancement. Clinical trial reporting guidelines, including CONSORT, establish common data elements that support systematic synthesis of published trial outcomes. However, the rapid rise of digital health technologies presents new challenges for reporting guidelines, and substantial real-world reporting heterogeneity has been observed. Therefore, machine-assisted evaluation of reporting adherence offers a pathway for more a…
An unmodified pretrained LLM performed screening and information extraction for digital health trial literature at F1 scores comparable to human inter-annotator agreement, suggesting faster evidence synthesis.
Evidence
- Peer-reviewedPLOS Digital Health2026-10-09
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Truvace Impact Record TRV-2026-1670, v1: “Retrieval-to-abstraction LLM-assisted literature synthesis: Case demonstrations in digital health technology-enabled randomized controlled trial outcome reporting.” Truvace, 2026-10-17. /record/TRV-2026-1670 (accessed at citation time). sha256 dec920dbb8ba8218…
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