Machine Learning Prediction of Anterior Open-Bite Development After Stabilization Splint Treatment in Temporomandibular Disorder
Objectives To develop interpretable machine learning (ML) models for risk stratification of clinically meaningful anterior overbite decrease after stabilization splint therapy in temporomandibular disorder (TMD) patients, and to compare ML performance with conventional logistic regression. Materials and methods This retrospective cohort included 87 TMD patients treated with stabilization splints, physical therapy, and pharmacologic therapy. Thirty-five pre-treatment cephalometric and demographic features were us…
Interpretable machine learning on pre-treatment cephalometric data separated higher-risk from lower-risk TMD patients better than logistic regression, which could support counseling and closer monitoring.
Regression models had near-zero or negative cross-validated R2 values, so exact overbite change could not be predicted from pre-treatment cephalometrics alone. The cohort was also small and retrospective.
Evidence
- Peer-reviewedClinical and Experimental Dental Research2026-10-01
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Truvace Impact Record TRV-2026-1570, v1: “Machine Learning Prediction of Anterior Open-Bite Development After Stabilization Splint Treatment in Temporomandibular Disorder.” Truvace, 2026-10-16. /record/TRV-2026-1570 (accessed at citation time). sha256 9c4e455e8eb57d71…
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