Comprehensive analysis and external validation of a glycolysis-related gene signature as a prognostic index for skin cutaneous melanoma
Skin cutaneous melanoma (SKCM) is the third most common cause of cancer-related deaths globally. Today, precise biomarkers to predict melanoma prognosis are quite limited. Aerobic glycolysis serves as the primary metabolic pathway for malignancies to meet their rapid growth demands. This study built a glycolysis-associated gene (GAG) signature to evaluate prognosis and immunotherapy response of SKCM. Data acquired from the Genotype-Tissue Expression (GTEx) and The Cancer Genome Atlas (TCGA) databases were evalua…
A four-gene glycolysis risk model built with machine learning effectively forecasted survival and treatment efficacy for skin cutaneous melanoma patients.
Evidence
- Peer-reviewedMelanoma Research2026-10-06
How should this claim be treated?
Truvace Impact Record TRV-2026-1322, v1: “Comprehensive analysis and external validation of a glycolysis-related gene signature as a prognostic index for skin cutaneous melanoma.” Truvace, 2026-10-11. /record/TRV-2026-1322 (accessed at citation time). sha256 5306d1fcb25b89cb…
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