aceExploring the Potential of Parent Report for Autism/Developmental Screening at the 18-Month Visit
Purpose To develop optimal algorithms of parent-administered items to improve the detection of autism and other developmental disorders at the 18-month visit. Methods Parents of 11,878 children aged 16-20 months completed the M-CHAT-R/F ™ , Q-CHAT-10-O, and ASQ-3 R at scheduled 18-month pediatric visits via an online system. Ninety-six children with positive screens and 314 matched controls completed additional items, including the POSI; items from the FYI and POEM data banks, and the MacArthur-Bates Communicati…
Parent-report ML model combining expressive vocabulary and joint attention items achieved over 0.7 sensitivity and specificity for both autism and developmental delay at 18-month visits, approximately doubling sensitivity versus existing screens.
Model training relied heavily on synthetic data generated from a small authentic subset and was evaluated on a limited holdback sample, constraining generalizability.
Evidence
- Peer-reviewedJournal of Autism and Developmental Disorders2026-09-28
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Truvace Impact Record TRV-2026-1218, v1: “Exploring the Potential of Parent Report for Autism/Developmental Screening at the 18-Month Visit.” Truvace, 2026-09-30. /record/TRV-2026-1218 (accessed at citation time). sha256 d2c17dd898987db1…
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