aceDistinct clinical patterns of preterm infants vulnerable to intestinal injury identified by unsupervised clustering
Background Current necrotizing enterocolitis (NEC) diagnostic criteria fail to capture the full spectrum of intestinal injury. We aimed to identify diagnosis-independent clinical patterns of intestinal injury among vulnerable very low birth weight (VLBW) infants using unsupervised hierarchical clustering. Methods Using prospectively collected data from 20,352 VLBW infants in the Korean Neonatal Network (2013-2022), unsupervised clustering was performed after excluding variables reflecting prematurity and NEC dia…
Unsupervised hierarchical clustering of 20,352 VLBW infants identified eight diagnosis-independent clusters of intestinal injury vulnerability, with high-risk Cluster 8 further split into five etiologic subclusters, creating a framework for a more precise taxonomy beyond traditional NEC staging.
Evidence
- Peer-reviewedPediatric Research2026-09-23
How should this claim be treated?
Truvace Impact Record TRV-2026-1201, v1: “Distinct clinical patterns of preterm infants vulnerable to intestinal injury identified by unsupervised clustering.” Truvace, 2026-09-27. /record/TRV-2026-1201 (accessed at citation time). sha256 252ca4d23c16943b…
Calibration history
Every change to this record since certification, in the open. None yet — the reading has held since it entered the record.
Certified into the record
How to verify without trusting this page
Fetch the canonical text of any version from /api/record/TRV-2026-1201 and hash it yourself — for example shasum -a 256 on the saved canonical field. The result must equal content_hash, and each version’s text ends with prev:followed by the prior version’s hash (version 1 chains to 64 zeros). If a single character of any version had been altered since certification, the chain would not reproduce.