aceGuideline Concordance of ChatGPT-Generated Responses on Antibiotic Prophylaxis in Endodontics
Antibiotic prophylaxis decision-making in endodontics represents a core competency in dental education, requiring the integration of systemic risk assessment, guideline interpretation, and antimicrobial stewardship principles. Although artificial intelligence (AI) tools such as ChatGPT are increasingly accessed by students and clinicians for clinical guidance, their educational reliability in teaching evidence-based antibiotic prophylaxis remains unclear. This descriptive study evaluated the accuracy and guideli…
ChatGPT-5 provided fully guideline-concordant answers in 10 of 17 endodontic antibiotic prophylaxis scenarios, performing best on classic teaching topics like infective endocarditis prophylaxis and antibiotic selection, dosage, and timing.
ChatGPT-5 unnecessarily expanded prophylactic indications in 4 scenarios and disagreed with guidelines in 3 scenarios involving immunocompromised patients, creating educational risk for inappropriate antibiotic prescribing.
Findings are limited to 17 predefined scenarios assessed by a single experienced endodontist and do not support conclusions about educational effectiveness or curricular implementation.
Evidence
- Peer-reviewedJournal of Dental Education2026-09-23
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Truvace Impact Record TRV-2026-1200, v1: “Guideline Concordance of ChatGPT-Generated Responses on Antibiotic Prophylaxis in Endodontics.” Truvace, 2026-09-27. /record/TRV-2026-1200 (accessed at citation time). sha256 cee23bbe99d5b337…
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