aceIdentification of key molecular targets in nicotine-induced spontaneous abortion through network toxicology and multi-omics integration
Introduction Spontaneous abortion (SA) remains a prevalent reproductive health challenge, with tobacco-derived nicotine emerging as a significant risk factor. This study sought to decipher the molecular underpinnings of nicotine-induced pregnancy loss through comprehensive multi-omics profiling to identify novel biomarkers and potential intervention targets. Methods An integrated bioinformatics approach was implemented combining network toxicology, transcriptomic profiling, and machine learning algorithms to elu…
Identification of key molecular targets in nicotine-induced spontaneous abortion through network toxicology and multi-omics integration: Introduction Spontaneous abortion (SA) remains a prevalent reproductive health challenge, with tobacco-derived nicotine emerging as a significant risk factor.
Evidence
- Peer-reviewedTobacco Induced Diseases2026-09-22
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Truvace Impact Record TRV-2026-1190, v1: “Identification of key molecular targets in nicotine-induced spontaneous abortion through network toxicology and multi-omics integration.” Truvace, 2026-09-26. /record/TRV-2026-1190 (accessed at citation time). sha256 7bdd298b5aa60502…
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