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record: TRV-2026-1163
version: 1
kind: certified
reason: Certified into the record
timestamp: 2026-09-22T06:53:28.259234Z
status: published
lens: p_space
sector: health
headline: An application of random forest regression for predicting healthcare costs using administrative databases
dek: Background Accurate healthcare cost predictions are essential for health economic decision-making. We propose a bottom-up approach that aggregates individual-level predictions to estimate expenditures for specific population segments without relying on a priori segmentation. Methods This retrospective population-based study used administrative healthcare data (2011-2023) from the Health Protection Agency of Bergamo (Italy). We traced 5-year healthcare resource utilization to predict individual's healthcare costs…
gain_title: (none)
problem_title: An application of random forest regression for predicting healthcare costs using administrative databases: Performance was assessed at the individual-level using error metrics, and at the population-level using prediction error (PE).
trace_subject: (none)
gain_reading: (none)
gain_evidence: (none)
problem_reading: An application of random forest regression for predicting healthcare costs using administrative databases: Performance was assessed at the individual-level using error metrics, and at the population-level using prediction error (PE).
problem_evidence: (none)
quick_read: Background Accurate healthcare cost predictions are essential for health economic decision-making. We propose a bottom-up approach that aggregates individual-level predictions to estimate expenditures for specific population segments without relying on a priori segmentation.

We traced 5-year healthcare resource utilization to predict individual's healthcare costs in the following year using random forest regression algorithms. Results At the individual-level, algorithms had a poor performance, systematically underestimating high-cost users.
limitation: 
tag: Evidence-backed problem
key_points: Background Accurate healthcare cost predictions are essential for health economic decision-making. | We propose a bottom-up approach that aggregates individual-level predictions to estimate expenditures for specific population segments without relying on a priori segmentation. | Methods This retrospective population-based study used administrative healthcare data (2011-2023) from the Health Protection Agency of Bergamo (Italy).
rundown: Background Accurate healthcare cost predictions are essential for health economic decision-making. We propose a bottom-up approach that aggregates individual-level predictions to estimate expenditures for specific population segments without relying on a priori segmentation.

Methods This retrospective population-based study used administrative healthcare data (2011-2023) from the Health Protection Agency of Bergamo (Italy). We traced 5-year healthcare resource utilization to predict individual's healthcare costs in the following year using random forest regression algorithms.
sources:
- peer_reviewed | Expert Review of Pharmacoeconomics & Outcomes Research | https://doi.org/10.1080/14737167.2026.2738028 | 2026-09-21
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