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TRV-2026-0920Certified recordPeer-reviewed

Association between body composition and recurrence in stage II-III colon cancer: a retrospective cohort study

Colorectal Cancer (CRC) is a common cause of cancer death and prognostic factors are used to determine management. Patients with advanced disease often become cachectic, losing skeletal muscle mass and density, as well as subcutaneous fat. CT can be used to assess body composition by measuring skeletal muscle area, density and subcutaneous and visceral fat. We hypothesise that evidence of sarcopenia or myosteatosis at diagnosis is associated with an increased risk of cancer recurrence. Patients discussed at the…

Health · The Trace — both readings · certified 2026-08-28 · v1 · article view · machine-readable

Current reading — gain

Using a machine learning model to measure CT body composition at L3 identified myosteatosis as an independent predictor of recurrence in stage II-III colon cancer.

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Patients with stage II-III colon cancer whose CT body composition showed myosteatosis via machine learning analysis had significantly lower 5-year recurrence-free survival.

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Truvace Impact Record TRV-2026-0920, v1: “Association between body composition and recurrence in stage II-III colon cancer: a retrospective cohort study.” Truvace, 2026-08-28. /record/TRV-2026-0920 (accessed at citation time). sha256 262955a4cbb875fb…

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