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TRV-2026-0917Certified recordPeer-reviewed

Noninvasive Profiling of the Glioma Vascular Microenvironment via 7T MRI: Decoding Angiogenic Signatures for Isocitrate Dehydrogenase and World Health Organization Grade Differentiation

Accurate preoperative glioma grading and molecular subtyping are important for treatment. The vascular microenvironment promotes tumor progression. A noninvasive screening tool capable of mapping tumor vascularity may assist in preoperative grading and subtyping of gliomas. To evaluate 7T susceptibility-weighted imaging (SWI) for differentiating glioma isocitrate dehydrogenase (IDH) status and World Health Organization (WHO) grade based on vascular microenvironment features. Retrospective. Among 218 patients wit…

Health · G Space — documented gain · certified 2026-08-28 · v1 · article view · machine-readable

Current reading — gain

Machine learning models using 7T SWI vascular topology, density and intensity features enabled noninvasive preoperative differentiation of glioma IDH status and WHO grade, with improved performance when integrated with clinical factors.

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Retrospective single-cohort design with only internal validation and no external or prospective testing reported, limiting generalizability of performance estimates.

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Truvace Impact Record TRV-2026-0917, v1: “Noninvasive Profiling of the Glioma Vascular Microenvironment via 7T MRI: Decoding Angiogenic Signatures for Isocitrate Dehydrogenase and World Health Organization Grade Differentiation.” Truvace, 2026-08-28. /record/TRV-2026-0917 (accessed at citation time). sha256 3d6c7e4e6cbaf2ad…

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