Intramuscular Fat Assessed by AI-Assisted Muscle Ultrasound: Association With Cardiometabolic Risk Factors and Diabetic Nephropathy in Diabetes Mellitus
Aims Intramuscular fat (IMF) is increasingly recognized as a marker of ectopic adiposity and adverse cardiometabolic outcomes. Artificial intelligence (AI)-assisted ultrasound of the rectus femoris (RF) offers a non-invasive approach for quantifying IMF. This study evaluated the association of IMF with diabetes-related complications (particularly diabetic nephropathy) and metabolic risk factors in patients with diabetes mellitus (DM). Materials and methods In this cross-sectional study, outpatients from a tertia…
AI-assisted ultrasound of the rectus femoris quantified intramuscular fat percentage (FATi), which was independently associated with diabetic nephropathy and adverse metabolic profiles in patients with diabetes.
Cross-sectional single-center design cannot establish causality or temporal role of IMF in complications; authors note need for longitudinal and multicentre validation.
Evidence
- Peer-reviewedDiabetes, Obesity and Metabolism2026-08-24
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Truvace Impact Record TRV-2026-0900, v1: “Intramuscular Fat Assessed by AI-Assisted Muscle Ultrasound: Association With Cardiometabolic Risk Factors and Diabetic Nephropathy in Diabetes Mellitus.” Truvace, 2026-08-26. /record/TRV-2026-0900 (accessed at citation time). sha256 dc80624eac49ef35…
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