aceQuality assessment of artificial intelligence responses in erectile dysfunction: a comparative study based on EAU recommendations
Artificial intelligence (AI)-based language models are increasingly explored as tools for interpreting and applying clinical guideline recommendations. In urology, the European Association of Urology (EAU) recently introduced a guideline-specific chatbot; however, its comparative performance relative to contemporary general-purpose large language models (LLMs) remains unclear. In this structured comparative study, five AI systems-the EAU Guidelines Bot, ChatGPT-5, Gemini 2.5 Pro, Copilot - Smart GPT-5, and Perpl…
Guideline-specific and general-purpose LLMs produced responses broadly consistent with EAU erectile dysfunction recommendations, with Gemini 2.5 Pro and EAU Guidelines Bot achieving the highest composite scores.
Performance varied significantly across models and domains, with Copilot and Perplexity scoring lower and greater inconsistency in clarity, structure, and clinical utility.
Findings are limited to structured guideline-derived scenarios and have not been validated in real-world clinical decision-making.
Evidence
- Peer-reviewedInternational Journal of Impotence Research2026-08-07
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Truvace Impact Record TRV-2026-0727, v1: “Quality assessment of artificial intelligence responses in erectile dysfunction: a comparative study based on EAU recommendations.” Truvace, 2026-08-10. /record/TRV-2026-0727 (accessed at citation time). sha256 85cfa848d4eac10f…
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